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Have you found that you are rarely or never “in the mood,” and can’t understand why? For some people, while they may wish that their sexual desire was higher, they struggle to become aroused. This can then cause problems with lubrication or erections, negatively impacting sexual enjoyment for both men and women.

For those struggling with sexual desire, peptide treatment is a way to increase sexual satisfaction by targeting the place where all sexual functions stem from, the brain.

What Are Peptides?

Peptides are short-chain amino acids connected by peptide bonds. Not only are they present in every cell in the body, but they also play a crucial role in most of the body’s functions. This is because they are signaling molecules used to communicate between different tissues, and they are also responsible for turning off specific functions in the body.

Some peptides include:

When it comes to sexual desire, bremelanotide (PT-141) is a peptide that has successfully been used to treat sexual dysfunction in men and women.

Signs of Sexual Dysfunction

The signs of sexual dysfunction can be divided based on gender:

Female Sexual Dysfunction

When a woman suffers from sexual dysfunction, she may experience a range of symptoms, such as:

Male Sexual Dysfunction

In men, sexual dysfunction is also known as erectile dysfunction (ED), which occurs when a man is unable to keep or maintain an erection during sexual activity. It’s a common condition that increases in prevalence as men get older.

One of the primary challenges with ED is that there are many potential causes of it. An erection relies on many different systems of the body, so a problem with one of them can then cause ED. For example, cardiovascular issues may cause blood flow to decrease, which can then impact a man’s erection.

Low libido is another contributor to ED, and it may be from low testosterone, or it may be from something else entirely.

Causes of Sexual Dysfunction

Sexual health significantly contributes to quality of life since it can affect a romantic relationship, sex life, and overall mood.

However, low libido, or low sexual desire, is a common problem within a relationship. Even more, it can be challenging to understand what causes this decline in sexual desire, as there are many contributors and it often has nothing to do with the romantic partner.

For example, sexual dysfunction can occur due to hormonal causes, such as when a woman goes through menopause or a man experiences declining testosterone levels. Besides sex hormones, the stress hormones of cortisol and adrenaline can also result in low libido, showing how chronic stress can affect your sexual function.

Low libido can also have psychological causes, such as depression. Additionally, some medications used to treat depression can lower libido even further.

The Impact of Low Sexual Desire

Hypoactive sexual desire disorder (HSDD), is a condition which occurs when someone has no (or very little) sex drive, and it bothers them. HSDD can affect both men and women, and it is the most common sexual problem for someone to have.

Those with HSDD have very little or no thoughts about sex and don’t respond to sexual signals or suggestions from their partner. Sometimes, those with HSDD may even have a low desire for sex while having it, and in many cases, they will avoid sex altogether.

HSDD can vary in how often it affects someone; it may be a problem all the time or only some of the time. Additionally, it could be a lifelong concern or something that increases in frequency with age.

Many things can cause HSDD, including:

When treating HSDD, peptide treatment is an effective solution that directly targets the problem of low sexual desire.

Peptide Therapy for Sexual Dysfunction

While sexual dysfunction may be due to physical problems with the body, in other cases, it can result from what is (or isn’t) happening in the brain. Sometimes there is something that keeps the brain from initiating arousal and desire, which are needed to induce an erection or increase lubrication.

To help incite desire, peptide therapy with PT-141 can help.

Unlike other treatments for sexual dysfunction, peptide therapy works on the central nervous system by increasing sexual desire and arousal. It accomplishes this by binding to the melanocortin receptors in the body, which can be found in the hypothalamus. These receptors help the body feel more aroused, so when PT-141 binds to them, sexual desire increases.

PT-141 may also activate dopamine, which is a type of neurotransmitter essential for pleasure and arousal.

Both of these actions of PT-141 can help set off a wave of arousal that boosts sex drive and readies the body’s physical response to sexual stimuli, such as lubrication or an erection. Those who try PT-141 can see sexual arousal within minutes or hours of treatment, and the results can last for hours.

Treatment with peptide therapy can improve lubrication, arousal, and orgasm in women. In men, peptide therapy helps to enhance sexual desire, erections, performance, and sex drive.

Looking Beyond the Vascular System

While the vascular system is responsible for helping a man obtain and maintain an erection, it has nothing to do with sexual desire. Because of this, treatments that target the vascular system, such as Viagra and Cialis, do nothing to increase libido.

Peptide treatment differs from these medications because it works with the nervous system to increase desire, arousal, and sexual satisfaction. Combining this with its ability to help a man achieve an erection, and your sex life can see a significant improvement.

Additionally, treatments for the vascular system are intended only for use by men, whereas peptide treatment assists both men and women suffering from sexual dysfunction.

Very few treatments exist for women with low libido, which makes peptide treatment so refreshing. Through this treatment, women become more empowered since they can regain control of their sex drive.

Treating Sexual Dysfunction with Peptides

If you suffer from sexual dysfunction due to low sexual desire, try peptide treatment. It directly targets the nervous system to increase sexual arousal, improve lubrication and erections, and increase overall sexual satisfaction. With peptide treatment, you can address the source of low libido and see improvement in all aspects of sexual function.

Reach out to Yugen Care to learn more about how peptide treatment can help you.


Parish, S., & Hahn, S. (2016). Hypoactive Sexual Desire Disorder: A Review of Epidemiology, Biopsychology, Diagnosis, and Treatment. Sexual Medicine Reviews, 4(2), 103-120. doi: 10.1016/j.sxmr.2015.11.009

MOLINOFF, P., SHADIACK, A., EARLE, D., DIAMOND, L., & QUON, C. (2003). PT-141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction. Annals Of The New York Academy Of Sciences, 994(1), 96-102. doi: 10.1111/j.1749-6632.2003.tb03167.x

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